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Thursday, 28 March 2013
How to Make Windows 8 Look and Feel Like Windows 7
Ford not 'yet' ready to talk 'Star Wars' sequels
LOS ANGELES (AP) ? Harrison Ford isn't ready ? "yet" ? to talk about his reported part in Disney's planned "Star Wars" sequel, but he praises its director, J.J. Abrams.
"I think he's fantastic," Ford said in a recent interview. "I did his first movie, 'Regarding Henry,' with Mike Nichols. A wonderful talent. Extraordinary guy."
The 70-year-old actor ? who came to fame playing Han Solo in the "Star Wars" trilogy ? is shrugging off questions about that character while promoting his role as Brooklyn Dodgers president Branch Rickey in the upcoming Jackie Robinson film "42."
Asked how he feels generally that the "Star Wars" sequel and Disney spinoffs are in the works, Ford responded: "I don't feel anything at the moment yet."
In an article published earlier this month, "Star Wars" creator George Lucas told Bloomberg Businessweek that Ford, Mark Hamill and Carrie Fisher had been in negotiations to return to the franchise even before Lucasfilm was sold to Disney last fall.
Was Ford surprised by that announcement? He makes the universal zipping-my-lips sign. Asked what it will take to get him to commit to play Han Solo again, Ford said, "Um, I don't even want to discuss that. It's great. Ain't it great?"
It's been over two decades since Abrams wrote the "Regarding Henry" screenplay. Have the two chatted recently?
"About what?" Ford asked, smirking and taking a slow sip from a cup.
____
Follow Ryan Pearson at http://www.twitter.com/ryanwrd
Source: http://news.yahoo.com/ford-not-yet-ready-talk-star-wars-sequels-130256296.html
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Alchemist Accelerator's Second Class Highlights 9 Enterprise Startups In Flight Data Tech, Learning Management And More
Here at the Citrix corporate headquarters for the presentations by the second class of the Alchemist Accelerator group. It's quite an eclectic class for the B2B accelerator.Source: http://feedproxy.google.com/~r/Techcrunch/~3/kxIPoTw2vak/
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Have Easter plans? Try these restaurants | Food and More with John ...
If you haven?t made reservations for a special Easter meal this Sunday, there may still be time. Here are some restaurants around town that will be celebrating the holiday.
103 West
Brunch buffet with kid-friendly fare and live entertainment. Activities for the children include bunny visits and face painting. 10:30 a.m. ? 3:00 p.m. $62 adults, $24.50 ages 6-12, free for 5 and under. 404-233-5993.
Antebellum
Sunday brunch menu from 9 a.m. ? 3 p.m. 770-965-8100
Bantam & Biddy
Special Easter meal served alongside regular menu. 11 a.m. ? 9 p.m. $20 Easter meal. 404-907-3469
Canoe
Holiday brunch menu from 10:30 a.m. ? 2:30 p.m. 770-432-2663
Chicken & the Egg
Sunday brunch menu served from 9:30 a.m. to 5 p.m. 678-388-8813
Ecco
Special brunch menu, 11 a.m. ? 3 p.m. 404-347-9555
Haven
Three-course brunch menu beginning at 10:30 a.m. $29.00, a la carte children?s menu will be available for $8.00 per item. 404-969-0700
Livingston Restaurant & Bar
Brunch buffet, $35 for adults, $15 for children ages 6-12, free under 5 years. 404-897-5000
No. 246
Brunch and lunch menus offered. Kids Easter egg hunt at 11 a.m. and 1 p.m. 678-399-8246
Ray?s on the Creek
Sunday brunch buffet served from 9 a.m. ? 3 p.m. $29.95 adults, $14.95 ages 5-10, 4 and under eat free. 770-649-0064
Ray?s on the River
Easter buffet served from 9 a.m. to 8 p.m. $39.95 adults, $19.95 children ages 5-10, 4 and under free. 770-955-1187
Rosebud
A la carte menu, 9 a.m. ? 4 p.m. 404-347-9747
South City Kitchen (both locations)
Three-course brunch menu staring at 10 a.m. (Vinings locations) and 11 a.m. (Midtown). $32, $16 children under 12. 404-873-7358 (Midtown) or 770-435-0700 (Vinings)
The Family Dog
No reservations accepted for this a la carte meal, 10:30 a.m. ? 4 p.m.
The Shed at Glenwood
Brunch buffet, 10 a.m. ? 3 p.m. $25 adult, $12 child. 404-835-4363
Valenza
Three-course Easter dinner with side items for the table to share starting at 5 p.m. $24. 404-969-3233
Villa Christina
Brunch buffet with complimentary mimosas. Activities for the kids include egg hunts, face painting, moon walk, Easter bunny photos and crafts. 11:30 a.m. ? 3:00 p.m. $45 adults, $25 children 6-12 years, free ages five and under. 404-303-0133
?by Jenny Turknett, Food & More blog
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Wednesday, 27 March 2013
Gene therapy may aid failing hearts
Mar. 25, 2013 ? In an animal study, researchers at the University of Washington show that it was possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions.
Led by University of Washington (UW) Professor and Vice Chair of Bioengineering Michael Regnier and Dr. Chuck Murry, director of the Center for Cardiovascular Biology and co-director of the Institute for Stem Cell and Regenerative Medicine at UW, the study appears online today in the journal Proceedings of the National Academy of Sciences (PNAS).
Normally, muscle contraction is powered by a molecule, the nucleotide called Adenosine-5'-triphosphate (ATP). Other naturally occurring nucleotides can also power muscle contraction, but, in most cases, they have proven to be less effective than ATP.
In an earlier study of isolated muscle, however, Regnier, Murry and colleagues had found that one naturally occurring molecule, called 2 deoxy-ATP (dATP), was actually more effective than ATP in powering muscle contraction, increasing both the speed and force of the contraction, at least over the short-term.
In the new PNAS study, the researchers wanted to see whether this effect could be sustained. To do this, they used genetic engineering to create a strain of mice whose cells produced higher-than-normal levels of an enzyme called Ribonucleotide Reductase, which converts the precursor of ATP, adenosine-5'-diphosphate or ADP, to dADP, which, in turn, is rapidly converted to dATP.
"This fundamental discovery, that dATP can act as a 'super-fuel' for the contractile machinery of the heart, or myofilaments, opens up the possibility to treat a variety of heart failure conditions," Regnier said. "An exciting aspect of this study and our ongoing work is that a relatively small increase in dATP in the heart cells has a big effect on heart performance."
The researchers found that increased production of the enzyme Ribonucleotide Reductase increased the concentration of dATP within heart cells approximately tenfold, and even though this level was still less than one to two percent of the cell's total pool of ATP, the increase led to a sustained improvement in heart muscle function, with the genetically engineered hearts contracting more quickly and with greater force.
"It looks as though we may have stumbled on an important pathway that nature uses to regulate heart contractility," Murry added. "The same pathway that heart cells use to make the building blocks for DNA during embryonic growth makes dATP to supercharge contraction when the adult heart is mechanically stressed."
Importantly, the elevated dATP effect was achieved without imposing additional metabolic demands on the cells, suggesting the modification would not harm the cell's functioning over the long-term.
The finding, the authors write, suggest that treatments that elevate dATP levels in heart cells may prove to be an effective treatment for heart failure.
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Story Source:
The above story is reprinted from materials provided by University of Washington - Health Sciences, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Sarah G. Nowakowski, Stephen C. Kolwicz, Frederick Steven Korte, Zhaoxiong Luo, Jacqueline N. Robinson-Hamm, Jennifer L. Page, Frank Brozovich, Robert S. Weiss, Rong Tian, Charles E. Murry, and Michael Regnier. Transgenic overexpression of ribonucleotide reductase improves cardiac performance. PNAS, March 25, 2013 DOI: 10.1073/pnas.1220693110
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/F2dumpqeqr0/130326101618.htm
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Tuesday, 26 March 2013
Cuba cleric: Francis criticized church at conclave
HAVANA (AP) ? Pope Francis issued a strong critique of the church before the College of Cardinals just hours before it selected him as the new pontiff, according to comments published Tuesday by a Roman Catholic magazine in Cuba.
According to Havana Cardinal Jaime Ortega, then-Cardinal Jorge Bergoglio urged the Vatican to eschew self-absorption and refocus its energies outward.
"The church is called on to emerge from itself and move toward the peripheries, not only geographic but also existential (ones): those of sin, suffering, injustice, ignorance and religious abstention, thought and all misery," Bergoglio said.
Ortega said Bergoglio's comments were made to cardinals as they gathered to select Benedict XVI's replacement, and reflect his vision of the contemporary Catholic Church. He said Bergoglio later gave him a handwritten version and permission to divulge its contents.
"Cardinal Bergoglio made a speech that I thought was masterful, insightful, engaging and true," Ortega said.
Ortega added that the remarks offer insight about the direction in which the new pope could take the church following his March 13 election.
In his statements, the future pontiff also warned of the dangers of stagnation.
"When the church does not emerge from itself to evangelize, it becomes self-referential and therefore becomes sick. ... The evils that, over time, occur in ecclesiastical institutions have their root in self-referentiality, a kind of theological narcissism." Bergoglio said.
He also criticized "a mundane church that lives within itself, of itself and for itself."
Finally Bergoglio said that whoever became the new pope should be "a man who ... helps the church to emerge from itself toward the existential outskirts."
Orgeta first revealed Bergoglio's comments in a weekend Mass, and they were published Tuesday on the website of Palabra Nueva magazine, along with a photo of the two men embracing after Bergoglio had donned the papal white robes and rechristened himself Francis.
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Health Care Reform: Who's responsible? - Real [Fit] Life
I just got back from the Business Review Power Breakfast at Glen Sanders Mansion. Today?s topic of discussion was Health Care at the Crossroads: The Drive Toward Reform.
I left feeling optimistic yet overlooked. Seriously. So much talk about numbers, expensive hospital additions, billion dollar?electronic health records, reimbursement models, and ER measurement?utilization, to name a few topics of discussion.?I?m sure if you were a large companies CEO in attendance you may have been impressed, but I wasn?t. Not entirely.
So why did I feel optimistic? A large part of New York State Commissioner of Health, Dr Nirav R. Shah?s message was appealing. I would like to have heard him speak more. I found it most interesting when he spoke of the necessary paradigm shift in ownership of health care and the necessity for businesses to start asking their providers ? what services will you provide to my employees to help keep them healthy?? This is refreshing since our culture has been ingrained to look at health insurance as something we mostly use when we get sick.
Preventative care. It?s the big buzz word as of late. As a fitness and wellness professional I am all on board.
But might I take that a step further and ask what the employers are doing to help keep their employees healthy?
Would that be too bold an assumption? I don?t think so.
Some companies are starting to take a deeper interest in their employees health because it affects their bottom line. The healthier your employees, the lower your insurance costs. Win win.
So companies are starting to look around and ask questions. What can I do to help my employees get healthier? Offer fitness classes? Offer monetary incentives like a deductible that can be put towards a gym membership or a deduction on their health insurance cost?
And furthermore, how do you measure that? How is one able to show that employees are actually getting healthier and that these programs are truly effective?
These are all great questions and I am glad they are finally being asked but can I also point out the irony?
The reason so many people are unhealthy in the first place is because of our work culture. The do more, do better, and do it faster mentality that every worker faces day to day.
CEO and President of St Peter?s Health Partners, James K. Reed, spoke on?today?s?panel as well. He did speak about doing more with less but he was referring to less medical procedures, like?unnecessary?MRI?s. He wasn?t referring to people. ?He also spoke of the need for better communication in the medical field on all levels. But I couldn?t help but feel that even that message did not include every day people like you and I.
And that is the problem. How do you get a whole community of people to care about being healthier if most of what you do is talk over their heads and about them merely as numbers? As dollars?
You don?t.
I see clients daily who are over worked, over stressed, under nourished, sleep deprived, extremely deconditioned, and over prescribed. These are well educated people with good paying jobs. They are doing it all and paying the price because it is what our culture expects.
Studies have shown that simply getting a good nights sleep on a regular basis can have worlds of impact on ones health in a positive way. That?s right. Sleep. But who?s got time for that, right? Seriously. I can imagine most of you laughing as you read this. Yet it is such a simple, free fix.
In addition, many people who are overweight are not eating enough calories or the right kind of calories for most of the day, and when they do eat, the choices are usually something quick and nutrient void. Why? It isn?t because they cannot afford healthy food. It?s because they are too busy.
I have clients who don?t even keep up with the renewal of their necessary medical prescriptions because, you guessed it, they are too busy.
So when I sit at a discussion such as the one I attended today, I think a large part of the puzzle is being overlooked. Businesses are now worrying as the health care system is changing. ?They suddenly can?t afford to have unhealthy employees. That?s great but you can?t just care about your bottom line. You have to truly care about your?people.
James Reed spoke of the greater need for compassion and connection from our doctors and nurses, for more effective communication. He also spoke of the desire for large companies to go to him directly to open up the discussion regarding medical care for their employees.
My question is: Who is talking to the employees? Who is showing them compassion? Who is truly investing in and opening up the discussion to them?
And this does not take the ownership away form the individual either. We are all in this together. And I think the Commissioner,Dr. Shah, did a fairly good job of trying to point that out.
But let?s face it. People spend most waking hours of their week at work. That is where a large part of their lives are spent. If employers can get their employees to make healthier choices in the work place, those benefits will carry over.
Offer on site fitness programming, health screenings, health education, and any other services that will help to make the lives of your employees less stressful and more productive. And offer incentives for participation. Get creative and also make it fun.
Human nature and resistance to change really were at the core of much of what was spoken about today. It?s normal. No one likes change. But people are much more likely to make that step towards it when you show a true investment in them rather than treating them solely as an investment.
www.realfitlife.com
Source: http://blog.timesunion.com/trimboli/health-care-reform-whos-responsible/3517/
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