Wednesday, 10 April 2013

Memories of My Grandmother's Cooking - Cuzco Eats

A Traditional Cuzco Grandmother

A Traditional Cuzco Grandmother

By Arnold Fernandez Coraza with the help of Walter Coraza Morveli (translated by David Knowlton)

From ancient times when the sun would come out and its rays shine on Cuzco, its light would show a beautiful scene of radiant trees and Andean fields all around the city. Back then agriculture and food was one of its privileges.

My grandparent?s land was huge. They would always plant and grow necessary foods such as potatoes, broad beans, and corn. These were basic and necessary for the daily, midday meal.

Potatoes Growing by a Home

Potatoes Growing by a Home

Along with breakfast, lunch was the essential mean to stay active during the day, until the last rays of the sun around five pm. When the sun would set they knew they had a brief moment to go have a quick lonche (small evening meal of a hot drink and bread or reheated food, from the English ?lunch?). Before it was completely dark they would go into their rooms and rest. There were no distractions to keep them up because in those days there was no light. They relied on rustic, kerosene lamps (mecheros) to have a little light at night.

Their land was very fertile. That enabled their crops to produce well and read full maturity. They would get a good harvest.

My grandparents always had hominy (mote) and boiled potatoes ready and waiting on the table. These would be in large receptacles. My uncles would eat them as appetizers before their main course at lunch, or whenever they had the urge during the day. Sometimes they would eat them with some cheese.

Lunch was always served at twelve noon, on the dot, not one minute early or one minute late. Their typical lunches would include soups like almuerzo de chu?o, made from freeze-dried potatoes, chairo, lawa de maiz (corn chowder), or wheat soup. These were served in large bowls so that my aunts and uncles could fill themselves and be well nourished.

The main dishes were called uchus, the same word as used to describe hot peppers. There would often be an aj? de lisas (ollucos), a main dish of tarwi, quinoa, a kapchi de habas, or others made from Andean products. They did not eat either rice or pasta.

All of their meals were cooked on wood fired fogones (stoves) and, as a result, they obtained particular flavors that are traditional in Cuzco and not available on modern stoves.

Most importantly, my grandmother would make sure their was more than enough food for everyone. It was the custom to have seconds and even thirds. And, in the evening, people would eat the left-overs from lunch.

Chicha was their main drink. It was never missing from the table for them to drink after having consumed their meals.

Cutting a Slice of the Traditional Lech?n

Cutting a Slice of the Traditional Lech?n

My grandmother would also raise animals around the home, such as guinea pigs, chickens, pigs, and ducks. These animals were kept because of their important for special dates, birthdays, and family gatherings. Every Sunday, when all the family would sit together, she would make something special. She would sacrifice one of her animals, maybe a delicious chicken that was well fed because it was cared for by her at home, or maybe some guinea pigs with which she would make a delicious pipian of cuy. She could also use other animals and make other dishes, depending on the event and the number of people.

She would serve the food in plates that were larger than those we use today. For my grandmother the plates had to be the largest ones she could find. Sometimes they looked like a medium sized wash basin.

As my uncles and aunts say, the food today can not compare with that of my grandmother?s times. Our food was unique and for that reason we have long lives. We were strong and healthy. When she was old, my grandmother would say ?look at my teeth. They are the same today as they have always been. I do not have any cavities.?

The family tells of all these moments as if they were reliving them. They remember their happy moments and their family gatherings when everyone would be there to enjoy my grandmother?s traditional dishes that are typical of our beautiful city.

Source: http://www.cuzcoeats.com/2013/04/memories-of-my-grandmothers-cooking/

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Lockup recommended for man who sneaked into jails

(AP) ? A man who repeatedly used phony credentials to gain entry into New York City's jails may get his wish to do more time.

Prosecutors told a judge on Thursday that they want Matthew Matagrano to be locked up for 10 years. Matagrano, a former inmate, pleaded not guilty to felony burglary in Manhattan Supreme Court.

The judge doubled his bail to $100,000 and ordered him to get medical attention.

The New York Post (http://bit.ly/ZbNv0w ) reports that according to police statements released in court, Matagrano said he repeatedly sneaked into jails because the people inside were "nice" and made him "feel important."

Authorities say Matagrano tried to get inside multiple city lockups, including Rikers Island and the Manhattan Detention Center, where he mingled with inmates for hours.

___

Information from: New York Post, http://www.nypost.com

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-04-05-Rikers%20Impersonator/id-cb222833601e4f20a8bed5460c4f6095

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Global burden of dengue is triple current estimates

Monday, April 8, 2013

The global burden of dengue infection is more than triple current estimates from the World Health Organization, according to a multinational study published today in the journal 'Nature'.

The research has created the first detailed and up-to-date map of dengue distribution worldwide, enabling researchers to estimate the total numbers of people affected by the virus globally, regionally and nationally. The findings will help to guide efforts in vaccine, drug and vector control strategies.

The study was led by Professor Simon Hay, a Wellcome Trust Senior Research Fellow at the University of Oxford, as part of the International Research Consortium on Dengue Risk Assessment, Management and Surveillance.

Dengue, also known as 'breakbone fever', is a viral infection that is transmitted between humans by mosquitoes. In some people, it causes life-threatening illness.

There are currently no licensed vaccines or specific treatments for dengue, and substantial efforts to control the mosquitoes that transmit the disease have not stopped its rapid emergence and global spread. Until now, little was known about the current distribution of the risk of dengue virus infection and its public health burden around the world.

Dr Samir Bhatt, who led the modelling for the study, says: "Our aim was to take all of the evidence that is currently available on the distribution of dengue worldwide and combine it with the latest in mapping and mathematical modelling to produce the most refined risk maps and burden estimates. We then hope to use this knowledge to help predict the future burden of the disease."

The findings reveal that dengue is ubiquitous throughout the tropics, with local spatial variations in risk influenced strongly by rainfall, temperature and urbanisation. The team estimate that there are 390 million dengue infections across the globe each year, of which 96 million reach any level of clinical or subclinical severity. This is more than triple the WHO's most recent estimates of 50-100 million infections per year.

Professor Simon Hay explains: "We found that climate and population spread were important factors for predicting the current risk of dengue around the world. With globalisation and the constant march of urbanisation, we anticipate that there could be dramatic shifts in the distribution of the disease in the future: the virus may be introduced to areas that previously were not at risk, and those that are currently affected may experience increases in the number of infections.

"We hope that the research will initiate a wider discussion about the significant global impact of this disease."

Of the 96 million apparent infections, Asia bore 70 per cent of the burden. India alone accounted for around one-third of all infections. The results indicate that with 16 million infections, Africa's burden is almost equivalent to that of the Americas and is significantly larger than previously appreciated. The authors suggest that the hidden African dengue burden could be a result of the disease being masked by symptomatically similar illnesses, under-reporting and highly variable treatment-seeking behaviour.

Professor Jeremy Farrar, Director of the Wellcome Trust Vietnam Research Programme and Oxford University Clinical Research Unit Hospital for Tropical Diseases in Vietnam, explains that the map and estimates produced by Hay's group set the benchmark for the disease: "This is the first systematic robust estimate of the extent of dengue. The evidence that we've gathered here will help to maximise the value and cost-effectiveness of public health and clinical efforts, by indicating where limited resources can be targeted for maximum possible impact

With endemic transmission in Asia and the Americas, recent outbreaks in Portugal, the ever-increasing incidence in Africa, and the challenges of making an effective dengue vaccine or controlling the vector, Professor Farrar stresses: "This really does represent a crucial period in the global spread of dengue."

Jimmy Whitworth, Head of International Activities at the Wellcome Trust, said: "Over time, this comprehensive map of global disease burden will also help to demonstrate which control measures are making the biggest difference in reducing the number of people suffering from dengue infection. Without a vaccine or specific treatment options, it's crucial that we understand where best to direct the limited resources available for preventing this resurgent disease."

###

Wellcome Trust: http://www.wellcome.ac.uk

Thanks to Wellcome Trust for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127625/Global_burden_of_dengue_is_triple_current_estimates

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89% Beyond The Hills

All Critics (75) | Top Critics (30) | Fresh (67) | Rotten (8)

The final shot, with windshield wipers struggling to clean away a torrent of muddy water, suggests that no human agency is great enough to handle this world's misery.

"Beyond the Hills" seethes with astonishment and rage at a broken society marooned between the 21st century and the 16th.

It is a haunting movie, dealing with superstitions, possession, even exorcism, one in which Mungiu poses no easy answers, because there are none to be found.

If you long for the bleak intelligence of an Ingmar Bergman film, where humankind is deeply flawed and God is indifferently silent and the landscape is cloaked in perpetual winter, then Beyond the Hills promises to be your cup of despair.

There are no easy villains or heroes in this sad and slow but forcefully told tale, which exhibits the same humanity Mungiu brought to 4 Months, 3 Weeks and 2 Days, his abortion drama that won the 2007 Palme d'Or.

A film that asks its viewer to consider the nature of good and evil, love and trust - and trust that turns into something like blind faith.

What makes this movie unique is that it holds literally everyone in the film accountable for the unfortunate goings on.

It's an exorcism movie for everyone who thought, after Mungiu's gruelling abortion buddy-movie 4 Months, 3 Weeks and 2 Days, that this guy should do an exorcism movie

It's an enigmatic and austere film from a region where political, sexual and religious repression are as stifling as the sooty air.

Mungui's rigorous approach to filmmaking isn't a ton of fun to watch, but his ideas stick with you.

It delivers an emotional punch, in what its director has called a story about the sin of indifference.

Such is the rigorous and high-minded nature of Romanian cinema that even a real-life exorcism story can inspire something loftier than a horror movie.

Heartbreak at a Romanian convent

...Cristian Mungiu has taken a real life event...to consider deeply human philosophies such as freedom vs. discipline, love vs. security, the choices facing those without financial recourse and the hypocrisies of organized religions.

I found it riveting to watch and fascinating to think about afterwards.

An undeniably tough watch.

Stark, deadpan, and darkly dry.

With this viscerally involving drama, acclaimed Romanian filmmaker Mungiu (4 Months, 3 Weeks and 2 Days) tells another strikingly original story of women caught between old and new world beliefs.

Mungiu is not preaching - he is telling us what can happen when people are trapped within their own emotions and circumstances. Remarkable.

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Source: http://www.rottentomatoes.com/m/beyond_the_hills_2012/

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Health and Fitness Talk ? Sickle Cell Disease

by Kimberly Allen, RN

Sickle cell disease (also called sickle cell anemia) is a blood disorder that is inherited.? It is a condition that affects mostly people of African descent, however, it also develops in other ethnic groups. ?There are over 70,000 Americans with sickle cell disease and approximately 2 million Americans that have the sickle cell trait.? Sickle cell disease is an autosomal recessive disorder which means it requires 2 abnormal genes, one from each parent.? Those that inherit 1 gene are carriers which is called having the sickle cell trait.
In sickle cell disease, there are not sufficient healthy red blood cells available to carry oxygen throughout the body.? Normal red blood cells are round and flexible allowing them to move easily through the blood vessels.? In a person that has sickle cell disease the red blood cells are sticky and rigid.? They are shaped like crescent moons or sickles thus the name sickle cell.? Because the red blood cells are sticky, rigid and irregularly shaped they tend to get stuck in the smaller blood vessels which slows and can even block the blood flow which in turn slows or blocks the oxygen from reaching parts of the body.? This can cause? significant pain as well as cause damage to muscles, organs and bones in your body.
sickle cellUsually the symptoms of sickle cell disease manifest after an infant has reached 4 months of age.? The major symptom is anemia.? Normal red blood cells have a life span of 120 days, then they die? and are replaced by new red blood cells.? In a person with sickle cell disease, the red blood cells affected only have a life span of 10-20 days.? Because they die off so quickly there are not enough new red blood cells to replace them which leaves them with a chronic shortage of red blood cells to deliver oxygen throughout their body, which in turn leads to chronic fatigue as well as? other symptoms of anemia.? People with sickle cell disease also experience episodes of severe pain.? These are known as sickle cell crises and occur because the sickle cells have? gotten stuck and blocked the blood flow throughout the small blood vessels located throughout areas of the body including the chest and abdomen as well as the joints.? Some people even need to be hospitalized in order to manage the crisis.? One of the first symptoms a parent may notice in an infant is swollen hands and feet caused by the sickle cell red blood cells obstructing the blood flow in and out of their hands and feet.? People with sickle cell disease are also more prone to infection because the spleen which helps to fight infection tends to become damaged by the sickle cells.? Children with sickle cell also tend to experience slowed growth and delayed puberty in teenagers.? Another problem that some people with sickle cell disease have is with the tiny blood vessels in their eyes.? If those blood vessels become blocked by the sickle cells the retina can be damaged causing vision problems.
Currently the only potential cure for sickle cell disease is a bone marrow transplant.? However, this is a very serious procedure that carries serious risks including potential death.? Because of this treatment for sickle cell disease usually focuses on avoiding crises, relieving symptoms and preventing complications.? People with sickle cell disease need to see their doctor regularly to have their blood checked and their overall health monitored.? Some doctors will recommend that children with sickle cell disease start taking penicillin when they?re 2 months old until they are at least 5 years old to help prevent serious infections like pneumonia.? For adults with sickle cell disease the doctor may recommend a medication called hydroxyurea which can help decrease the need for blood transfusions and reduce the frequency of crises.? Because hydroxyurea increase your chances of developing an infection it is only recommended for adults.? There have also been some concerns raised that long-term use on this medication may cause leukemia or tumors in some people.? Your doctor will be able to help you decide if this medication will benefit you.

Kimberly Allen is a registered nurse with an AND in nursing. She has worked in ACF, LCF and psychiatric facilities, although she spent most of her career as a home health expert. She is now a regular contributor to HealthAndFitnessTalk.com, dispensing advice and knowledge about medical issues and questions. You can reach her with any comments or questions at? mussatti3@gmail.com.

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Source: http://www.healthandfitnesstalk.com/sickle-cell-disease/

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Researchers create next-generation Alzheimer's disease model

Apr. 9, 2013 ? A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer's disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease, according to a study, published in the Journal of Neuroscience. The study was supported by the National Institutes of Health.

"We believe the rats will be an excellent, stringent pre-clinical model for testing experimental Alzheimer's disease therapeutics," said Terrence Town, Ph.D., the study's senior author and a professor in the Department of Physiology & Biophysics in the Zilkha Neurogenetic Institute at the University of Southern California Keck School of Medicine, Los Angeles.

Alzheimer's is an age-related brain disorder that gradually destroys a person's memory, thinking, and the ability to carry out even the simplest tasks. Affecting at least 5.1 million Americans, the disease is the most common form of dementia in the United States. Pathological hallmarks of Alzheimer's brains include abnormal levels of beta-amyloid protein that form amyloid plaques; tau proteins that clump together inside neurons and form neurofibrillary tangles; and neuron loss. Additionally, glial cells -- which normally support, protect, or nourish nerve cells -- are overactivated in Alzheimer's.

Plaque-forming beta-amyloid molecules are derived from a larger protein called amyloid precursor protein (APP). One hypothesis states that increases in beta-amyloid initiate brain degeneration. Genetic studies on familial forms of Alzheimer's support the hypothesis by linking the disease to mutations in APP, and to presenilin 1, a protein thought to be involved in the production beta-amyloid.

Researchers often use rodents to study diseases. However, previous studies on transgenic mice and rats that have the APP and presenilin 1 mutations only partially reproduce the problems caused by Alzheimer's. The animals have memory problems and many plaques but none of the other hallmarks, especially neurofibrillary tangles and neuron loss.

To address this issue, Dr. Town and his colleagues decided to work with a certain strain of rats.

"We focused on Fischer 344 rats because their brains develop many of the age-related features seen in humans," said Dr. Town, who conducted the study while working as a professor of Biomedical Sciences at Cedars-Sinai Medical Center and David Geffen School of Medicine at the University of California, Los Angeles.

The rats were engineered to have the mutant APP and presenilin 1 genes, which are known to play a role in the rare, early-onset form of Alzheimer's. Behavioral studies showed that the rats developed memory and learning problems with age. As predicted, the presence of beta-amyloid in the brains of the rats increased with age. However, unlike previous rodent studies, the rats also developed neurofibrillary tangles.

"This new rat model more closely represents the brain changes that take place in humans with Alzheimer's, including tau pathology and extensive neuronal cell death," said Roderick Corriveau, Ph.D., a program director at NIH's National Institute of Neurological Disorders and Stroke. "The model will help advance our understanding of the various disease pathways involved in Alzheimer's onset and progression and assist us in testing promising interventions."

The researchers performed a variety of experiments confirming the presence of neurofibrillary tangles in brain regions most affected by Alzheimer's such as the hippocampus and the cingulate cortex, which are involved in learning and memory. Further experiments showed that about 30 percent of neurons in these regions died with age, the largest amount of cell death seen in an Alzheimer's rodent model, and that some glial cells acquired shapes reminiscent of the activated glia found in patients.

"Our results suggest that beta-amyloid can drive Alzheimer's in a clear and progressive way," said Dr. Town.

Activation of glia occurred earlier than amyloid plaque formation, which suggests Dr. Town and his colleagues identified an early degenerative event and new treatment target that scientists studying other rodent models may have missed.

The findings support a prime research objective identified during the May 2012, NIH-supported Alzheimer's Disease Research Summit 2012: Path to Treatment and Prevention, an international gathering of Alzheimer's researchers and advocates. Improved animal models were cited as key to advancing understanding of this complex disease.

"To fully benefit from this exciting new work, there is a critical need to share the animal model with researchers dedicated to finding ways to delay, prevent or treat Alzheimer's disease'' said Neil Buckholtz, Ph.D., of the National Institute on Aging, which leads the NIH effort in Alzheimer's research. "Accordingly, Dr. Town and his colleagues are working towards making their new rat model easily accessible to the research community."

In addition to grants from NINDS (NS076794), NIA (AG029726, AG033394) and the NIMH Intramural Research Program, this study was funded by the Alzheimer's Association (IIRG-05-14993, ZEN-10-174633) and the Ellison Foundation/American Federation for Aging Research (M11472).

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The above story is reprinted from materials provided by NIH/National Institute of Neurological Disorders and Stroke.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Cohen RM et al. A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric A? and frank neuronal loss. Journal of Neuroscience, April 10, 2013 DOI: 10.1523/JNEUROSCI.3672-12.2013

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/WI4UTPqjdDY/130409173455.htm

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Tuesday, 9 April 2013

Twitter gatecrashers destroy home: key lessons - AOL Money UK

Twitter logoDominic Lipinski/PA Wire

A family in Enderby, Leicestershire, is facing a bill of ?3,500 to repair damage to their home, after a party was advertised at the house on Twitter, and 100 gatecrashers showed up.

So what happened, and how can you protect your home?

Trashed

The worrying part of this story is that the party was not advertised by 16-year-old Brodie Norman, or any of her close friends. However, someone issued a general invitation to her property - giving the address - and inviting them for the evening of 31 March. According to This Is Leicestershire, between 80 and 100 people showed up.

Her parents, Kevin and Lesley Norman, were out at the time. They returned to find food smeared all over their home, wardrobes emptied and clothes thrown everywhere, an antique chair smashed, and ornaments broken.

Mr Norman told the Daily Telegraph: "The trouble was caused by people who just turned up because someone put it out on Twitter. It was mayhem but my daughter and her friends were too scared to do anything."

This is Leicestershire said the parents had contacted the parents of those they believe were involved.

Protect your home

This isn't the first party to have led to disaster after being advertised on social media. We reported at the end of last year about the lottery winner's daughter who mentioned a party on Facebook, and had 200 gatecrashers.

Perhaps the most famous example was in Haren in Holland last October, when 3,000 showed up to a party advertised on Facebook, and when police intervened it led to riots and looting.

If your party is advertised online, then your insurer may well argue that you were inviting strangers into your home - and they may refuse to pay out for the damage - so prevention is the only solution.

The answer is simply that parties cannot be advertised on any social media site. Even a private invitation to friends or a casual mention of a party you are planning are not a good idea unless you want gatecrashers - because invitations are just too easy to forward on to everyone else. If you know someone well enough to invite them to a party, then you'll know them well enough to do it in person or by phone.

If the message leaks out somehow online, then you don't have a choice - you need to cancel the party. If you cancel the event and inform police, they will be on stand-by to turn any gatecrashers away.

You may think this is something you only need to worry about with older kids - but 'Project X' parties - where gatecrashing and destruction are planned by strangers - can happen at any age. In December last year a 14-year-old in Essex organised a party on Facebook, which caused ?30,000 of damage to the family home.

Source: http://money.aol.co.uk/2013/04/08/twitter-gatecrashers-destroy-home-key-lessons/

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